Research Communications of the 27(th) ECVIM-CA Congress: Intercontinental, Saint Julian's, Malta, 14th to 16th September 2017

Disclosures: Disclosures to report. Funding from the co-authors include funding from the Australian research Council, Canine Health Foundation, Canine Research Foundation, Hills Pet Nutrition, NexVet Biologics and PlasVacc. None of this funding is directly related to this project. None of the authors have shares, receive consulting fees or have financial interests with any company. Neither do family members. The indirect immunofluorescence (IIF)-ANA test is the standard method for detecting ANAs. Further testing for ANA specificities with different techniques, such as ELISAs, immunoblot or immunodiffusion, is routinely performed in humans, but not in dogs, to aid in the diagnosis of disease. Several specific ANAs identified in humans have been identified also in suspected canine SLE or SLErelated disorders but in many cases the main antigen targeted by the antibodies cannot be identified. IIF-ANA positive dogs are usually divided into two subgroups depending on their fluorescence pattern, a speckled pattern with no chromosomal reactivity or a homogenous pattern with chromosomal reactivity. Previous studies have shown that only dogs with a speckled IIF-ANA pattern are positive on immunodiffusion.