Selected article for: "clinical suspicion and differential diagnosis"

Title: Research Communications of the 27(th) ECVIM-CA Congress: Intercontinental, Saint Julian's, Malta, 14th to 16th September 2017
  • Document date: 2017_11_7
  • ID: roslkxeq_438
    Snippet: Disclosures: No disclosures to report. Clinical diagnosis of pancreatitis in cats is challenging. Clinical signs are non-specific, and most available serum tests, including serum amylase and lipase activities and feline trypsin-like immunoreactivity (fTLI) lack specificity and/or sensitivity in this species. Serum specific feline pancreatic lipase (Spec fPL) is currently the most useful serum test for pancreatitis in cats. Based on this test, a r.....
    Document: Disclosures: No disclosures to report. Clinical diagnosis of pancreatitis in cats is challenging. Clinical signs are non-specific, and most available serum tests, including serum amylase and lipase activities and feline trypsin-like immunoreactivity (fTLI) lack specificity and/or sensitivity in this species. Serum specific feline pancreatic lipase (Spec fPL) is currently the most useful serum test for pancreatitis in cats. Based on this test, a rapid, in-clinic, semi-quantitative test for the estimation of fPL (SNAP fPL TM ) in serum has been developed. Currently, no studies have evaluated the sensitivity and specificity of this tool for pancreatitis in cats. The aim of this study was to evaluate the specificity of SNAP fPL in two groups of cats: a) healthy cats and b) sick cats without clinical suspicion of pancreatitis. A total of 196 cats were included in the study. Of them, 105 were clinically healthy (based on history and physical examination) and 91 cats were sick. The group of sick cats consisted of cats with a wide variety of diseases, for which pancreatitis was not considered a major differential or for which a final diagnosis other than pancreatitis that would explain the clinical signs was available. Whole blood was collected from all cats, and serum was separated and stored until analysis. The SNAP fPL test was performed and interpreted according to the manufacturer's instructions. Specificity was calculated for each group of cats separately and for both groups combined.

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