Selected article for: "human idiopathic pulmonary fibrosis and pulmonary fibrosis"
Title: RESEARCH COMMUNICATIONS OF THE 28th ECVIM-CA CONGRESS
  • Document date: 2018_12_19
    • ID: r79h9yzz_1051
    Snippet: Canine idiopathic pulmonary fibrosis (CIPF), affecting mainly West Highland White Terriers (WHWTs,) is a chronic progressive interstitial lung disease sharing many similarities with human idiopathic pulmonary fibrosis (IPF). CIPF is characterized by exaggerated accumulation of extracellular matrix (ECM) in the lung parenchyma. Matrix‐metalloproteinases (MMPs) are proteolytic enzymes capable of degrading ECM. In human IPF, MMP‐7 has been found.....
    Document: Canine idiopathic pulmonary fibrosis (CIPF), affecting mainly West Highland White Terriers (WHWTs,) is a chronic progressive interstitial lung disease sharing many similarities with human idiopathic pulmonary fibrosis (IPF). CIPF is characterized by exaggerated accumulation of extracellular matrix (ECM) in the lung parenchyma. Matrix‐metalloproteinases (MMPs) are proteolytic enzymes capable of degrading ECM. In human IPF, MMP‐7 has been found to be a potential diagnostic and prognostic biomarker. The aim of this study was to compare MMP‐7 activities in serum of CIPF WHWTs, healthy WHWTs and other breed healthy dogs.

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