RESEARCH COMMUNICATIONS OF THE 28th ECVIM-CA CONGRESS

Client‐owned dogs were recruited. The inclusion criteria for Leish‐dogs (L‐group) were a definitive diagnosis of leishmaniasis and an allopurinol treatment of at least one month. The controlled dogs (C‐group) where clinically healthy, and had a negative serological test for Leishmania infantum. The exclusion criteria were a severe hepatic disease, breeds predisposed to NRO urolithiasis and low purine diets. Complete clinical and blood analysis data were collected. Abdominal ultrasonography was systematically performed, and if calculi above 2 millimeters were identified, abdominal radiographs completed the study. All images were recorded and secondly blindly reviewed by the same board certified radiologist in all dogs. Urine was collected for classical urinalysis, xanthine measurement, urine xanthine/creatinine (UXC) ratio and infrared spectrometry of the urine sediment.