Title: RESEARCH COMMUNICATIONS OF THE 28th ECVIM-CA CONGRESS Document date: 2018_12_19
ID: r79h9yzz_558
Snippet: Angiogenesis is essential for tumor progression, and microvessel density is known as a prognostic factor for many solid tumors. Recently, antiâ€angiogenic therapy has been a potential therapeutic strategy for various types of tumor. Histological assessment has only been reported for evaluating the angiogenesis in current veterinary medicine. For this reason, evaluating the angiogenesis is difficult in patients without surgery. Therefore, a novel.....
Document: Angiogenesis is essential for tumor progression, and microvessel density is known as a prognostic factor for many solid tumors. Recently, antiâ€angiogenic therapy has been a potential therapeutic strategy for various types of tumor. Histological assessment has only been reported for evaluating the angiogenesis in current veterinary medicine. For this reason, evaluating the angiogenesis is difficult in patients without surgery. Therefore, a novel evaluation method is needed. The aim of this study was to assess whether histological measurements of blood vessels is associated with mRNA levels of endothelial markers such as vWF and endoglin in spontaneous canine tumors. Additionally, we investigated the relationships between endothelial markers and angiogenic factors such as vascular endothelial growth factor (VEGF) and VEGF receptor2 (VEGFR2).
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