Title: RESEARCH COMMUNICATIONS OF THE 28th ECVIM-CA CONGRESS Document date: 2018_12_19
ID: r79h9yzz_784
Snippet: Atrial fibrillation (AF) is the most common heart rhythm disturbance associated with poor prognosis and outcome encountered in clinical practice in dogs. While structural and electrical remodeling of the atria is a well known factor facilitating initiation and maintenance of AF, little is known about the role of oxidative stress in this process. Uric acid (UA) is the terminal enzymatic product of purine metabolism. In humans, the serum UA level i.....
Document: Atrial fibrillation (AF) is the most common heart rhythm disturbance associated with poor prognosis and outcome encountered in clinical practice in dogs. While structural and electrical remodeling of the atria is a well known factor facilitating initiation and maintenance of AF, little is known about the role of oxidative stress in this process. Uric acid (UA) is the terminal enzymatic product of purine metabolism. In humans, the serum UA level is strongly correlated with cardiovascular risk factors, including the risk of atrial fibrillation. It is also considered a marker of increased oxidative stress via the xanthine oxidase pathway.
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