Title: RESEARCH COMMUNICATIONS OF THE 28th ECVIM-CA CONGRESS Document date: 2018_12_19
ID: r79h9yzz_902
Snippet: Canine B cell neoplasms (insulinomas) are the most frequent neuroendocrine tumor in the pancreas. They secrete excessive amounts of insulin which leads to hypoglycemia and the subsequent clinical signs. In humans, a multitargeted tyrosine kinase inhibitor (sunitinib) has proven efficacy in patients with pancreatic neuroendocrine tumors. Anecdotal reports suggest an antitumor activity of toceranib phosphate in dogs with insulinomas......
Document: Canine B cell neoplasms (insulinomas) are the most frequent neuroendocrine tumor in the pancreas. They secrete excessive amounts of insulin which leads to hypoglycemia and the subsequent clinical signs. In humans, a multitargeted tyrosine kinase inhibitor (sunitinib) has proven efficacy in patients with pancreatic neuroendocrine tumors. Anecdotal reports suggest an antitumor activity of toceranib phosphate in dogs with insulinomas.
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