Risk factors for severe bronchiolitis caused by respiratory virus infections among Mexican children in an emergency department

Robledo-Aceves, Mireya; Moreno-Peregrina, María de Jesús; Velarde-Rivera, Fernando; Ascencio-Esparza, Elba; Preciado-Figueroa, Francisco M.; Caniza, Miguela A.; Escobedo-Melendez, Griselda

It is important to note that we did not find an association for severe bronchiolitis among cases of children with severe bronchiolitis with viral coinfections, as has been reported previously. [28] Our findings also contrasted with previous reports in which rhinovirus and metapneumovirus were the most frequent viruses isolated from children with bronchiolitis. [11, 22, 28] In addition, is contrasting with our study the fact of metapneumovirus and adenovirus were the respiratory virus reported most frequently in Mexican children (under 5 years of age) who had acute respiratory infection during winter and spring, and did not require being hospitalized in Emergency department. [32] Although we detected rhinovirus, PIV type 3, and other respiratory viruses in the children with severe bronchiolitis in our study, further large-scale investigations are necessary to estimate the prevalence of these respiratory viruses in different pediatric settings and their implications in the severity of respiratory infections.