Author: Kleinman, Steve; Stassinopoulos, Adonis
Title: Risks associated with red blood cell transfusions: potential benefits from application of pathogen inactivation Document date: 2015_8_25
ID: qlddzgbg_13
Snippet: indicating an incidence of about one case annually. 49, 51 Similar to B. microti, these observations illustrate how increased scrutiny may uncover a pathogen prevalence and level of risk that had previously escaped the attention of public health and transfusion medicine specialists. Currently, there is no blood donor screening for this agent. 60 However, such deferrals have inherent nonspecificity and may require periodic revision to account for .....
Document: indicating an incidence of about one case annually. 49, 51 Similar to B. microti, these observations illustrate how increased scrutiny may uncover a pathogen prevalence and level of risk that had previously escaped the attention of public health and transfusion medicine specialists. Currently, there is no blood donor screening for this agent. 60 However, such deferrals have inherent nonspecificity and may require periodic revision to account for new epidemics. Extrapolating from data showing the effectiveness of PLT and plasma PI 61,62 against these agents, a reasonable assumption is that PI-RBC technology will also be effective. If so, application of PI to all components could obviate the need for EIA-related travel deferral.
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