Selected article for: "body weight and significant change"
Author: Dziwenka, Margitta; Coppock, Robert; Alexander, McCorkle; Palumbo, Eddie; Ramirez, Carlos; Lermer, Stephen
Title: Safety Assessment of a Hemp Extract using Genotoxicity and Oral Repeat-Dose Toxicity Studies in Sprague-Dawley Rats
  • Document date: 2020_2_20
    • ID: u9msvq70_49
    Snippet: In the 90-day study being reported here, test article related significant changes in body weights, daily body weight gain and feed efficiency were seen in the males in all treatment groups which was still noted at the end of the recovery period. The magnitude of the significant change in body weights, daily body weight gain and feed efficiency in the low and mid dose groups was less than 10% and showed signs of obvious recovery and were therefore.....
    Document: In the 90-day study being reported here, test article related significant changes in body weights, daily body weight gain and feed efficiency were seen in the males in all treatment groups which was still noted at the end of the recovery period. The magnitude of the significant change in body weights, daily body weight gain and feed efficiency in the low and mid dose groups was less than 10% and showed signs of obvious recovery and were therefore considered to be not toxicologically relevant. The effect in the males receiving 800 mg/kg/ day was > 10% and was still evident at the end of the recovery period and was considered toxicologically relevant.

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