Selective anchoring in the specific plasma membrane domain: a role in epithelial cell polarity

that it reflects variation between cells (86), but in a confluent epithelial monolayer we cannot discriminate whether neighboring spots would reflect conditions in the same cell or in closely adjacent cells, specially for the basolateral domain where interdigitations are frequently observed. Hence, we do not have direct evidence in this system on whether TIF reports on heterogeneity in the cell population or microheterogeneity in the mobility of the proteins within the membrane surface of a given cell. A2 fluorescence recovered in all cells labeled with Fab (TIF = 0; Table IV) . On the other hand, B1 and B2-m showed 28 and 52% of the cells, respectively, failing to recover any fluorescence at all on the basolateral membrane.