Author: Nicholls, John M
Title: The Battle Between Influenza and the Innate Immune Response in the Human Respiratory Tract Document date: 2013_3_29
ID: vyci1ho3_29
Snippet: Once influenza encounters the cell there are pattern recognition receptors (PRR) that are stimulated to initiate an antiviral response leading to the production of interferon and cytokines and chemokines. The three main pathways that are triggered leading to an interferon response are the toll like receptor pathway (TLR), retinoic acid inducible gene I (RIG-I) like receptors (RLR), and nucleotide oligomerization domain (NOD)-like receptor pathway.....
Document: Once influenza encounters the cell there are pattern recognition receptors (PRR) that are stimulated to initiate an antiviral response leading to the production of interferon and cytokines and chemokines. The three main pathways that are triggered leading to an interferon response are the toll like receptor pathway (TLR), retinoic acid inducible gene I (RIG-I) like receptors (RLR), and nucleotide oligomerization domain (NOD)-like receptor pathway pyrin domain containing 3 (NLRP3) (reviewed in van de Sandt [54] ).
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