Selected article for: "human human and infected canine"
Author: Zahoor, Bilal A.; Mudie, Lucy I.
Title: The imperative to develop a human vaccine for the Hendra virus in Australia
  • Document date: 2015_10_29
    • ID: wu77xf6c_6
    Snippet: The efficacy of the equine HeV vaccine, in preventing human HeV infection, relies on the assumption that the equine serves as the sole intermediary host for human HeV infection (3) . Accordingly, this does not factor in the possible host amplification and the subsequent mutation of zoonotic diseases which can precipitate a human HeV infection and possible epidemic. To date, no index cases of human-to-human transmission of HeV have been documented.....
    Document: The efficacy of the equine HeV vaccine, in preventing human HeV infection, relies on the assumption that the equine serves as the sole intermediary host for human HeV infection (3) . Accordingly, this does not factor in the possible host amplification and the subsequent mutation of zoonotic diseases which can precipitate a human HeV infection and possible epidemic. To date, no index cases of human-to-human transmission of HeV have been documented. However, the emergence of atypical presentations: asymptomatic equine, infected canine, and outlier cases readily supports that HeV is mutating rapidly and is seeking new co-hosts. This pattern is clearly evidenced, in other similar bat-related zoonotic infections, namely the recent Ebola epidemic and the 2014 Middle East respiratory syndrome coronavirus (MERS-CoV) epidemic (4, 12) .

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