Author: Thornton, Hannah V; Hay, Alastair D; Redmond, Niamh M; Turnbull, Sophie L; Christensen, Hannah; Peters, Tim J; Leeming, John P; Lovering, Andrew; Vipond, Barry; Muir, Peter; Blair, Peter S
Title: Throat swabs in children with respiratory tract infection: associations with clinical presentation and potential targets for point-of-care testing Document date: 2017_2_18
ID: r3fzwy00_44
Snippet: In the absence of a gold standard single sample site from the upper respiratory tract, we took a pragmatic decision to use throat swabs for microbial detection as we judged them to be the sampling method most acceptable to parents and busy primary care clinicians. We acknowledge that, although we might have achieved significantly lower sampling rates, samples obtained and pooled from the oropharynx, nasopharynx and nares could have mitigated the .....
Document: In the absence of a gold standard single sample site from the upper respiratory tract, we took a pragmatic decision to use throat swabs for microbial detection as we judged them to be the sampling method most acceptable to parents and busy primary care clinicians. We acknowledge that, although we might have achieved significantly lower sampling rates, samples obtained and pooled from the oropharynx, nasopharynx and nares could have mitigated the known problem of different optimal sample sites for different microbes (15) and might have produced more sensitive and specific results for some microbes.
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