Author: Seemann, Stefan E.; Gorodkin, Jan; Backofen, Rolf
Title: Unifying evolutionary and thermodynamic information for RNA folding of multiple alignments Document date: 2008_10_4
ID: wtvfow2f_51
Snippet: The suggested PETfold parameters are based on the average performance over all RNA families in the data set. We observed a common distribution of PETfold performance for different parameter settings in which low-reliability thresholds for evolutionary substructures rel decrease the prediction accuracy ( Figure 1) . Thus, the general application of evolutionary constraints has negative influences on the structure prediction......
Document: The suggested PETfold parameters are based on the average performance over all RNA families in the data set. We observed a common distribution of PETfold performance for different parameter settings in which low-reliability thresholds for evolutionary substructures rel decrease the prediction accuracy ( Figure 1) . Thus, the general application of evolutionary constraints has negative influences on the structure prediction.
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