Author: Wang, Shiliang; Sundaram, Jaideep P.; Stockwell, Timothy B.
Title: VIGOR extended to annotate genomes for additional 12 different viruses Document date: 2012_6_4
ID: wd3ir3wg_41
Snippet: A total of 568 genes were predicted by VIGOR from 50 RSV genomes, and 522 genes predicted by VIGOR were the same as the annotations in GenBank. The start codons of 13 genes defined by VIGOR were different from GenBank annotations. All of these are M2-2 gene. Similar to the M2-1 protein in MPV, two versions of M2-2 protein exist in GenBank protein database. The longer version has two additional amino acids at the N-terminus. VIGOR picked the longe.....
Document: A total of 568 genes were predicted by VIGOR from 50 RSV genomes, and 522 genes predicted by VIGOR were the same as the annotations in GenBank. The start codons of 13 genes defined by VIGOR were different from GenBank annotations. All of these are M2-2 gene. Similar to the M2-1 protein in MPV, two versions of M2-2 protein exist in GenBank protein database. The longer version has two additional amino acids at the N-terminus. VIGOR picked the longer version as the reference sequence to define the start codon. VIGOR also predicted 33 genes that were not annotated in GenBank. All of these 33 new genes were the M2-2 and M1-2 genes.
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