Author: Christensen, Maria H; Paludan, Søren R
Title: Viral evasion of DNA-stimulated innate immune responses Document date: 2016_3_14
ID: pvdlox4j_17
Snippet: DNA is a highly immunostimulatory molecule, and the immune responses evoked by DNA have antiviral activity. Consequently microbes with DNA genomes have evolved mechanisms to evade sensing and signaling through the pathways stimulated by DNA. This is probably of central importance for the ability of DNA viruses to establish infection, and underscores the importance of the DNA-stimulated immune pathways in protective immunity......
Document: DNA is a highly immunostimulatory molecule, and the immune responses evoked by DNA have antiviral activity. Consequently microbes with DNA genomes have evolved mechanisms to evade sensing and signaling through the pathways stimulated by DNA. This is probably of central importance for the ability of DNA viruses to establish infection, and underscores the importance of the DNA-stimulated immune pathways in protective immunity.
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