Author: Corey M Peak; Lauren M Childs; Yonatan H Grad; Caroline O Buckee
Title: Containing Emerging Epidemics: a Quantitative Comparison of Quarantine and Symptom Monitoring Document date: 2016_8_31
ID: 2j4z5rp8_9
Snippet: Here we develop an agent-based branching model that accommodates realistic distributions of disease characteristics and maintain the infector-infectee correlation 6 structure necessary for interventions targeted via contact tracing. To assess diseases with a wide range of natural histories that have the potential for causing sudden, severe epidemics, we consider case studies of seven known pathogens: Ebola; hepatitis A; influenza A; Middle East R.....
Document: Here we develop an agent-based branching model that accommodates realistic distributions of disease characteristics and maintain the infector-infectee correlation 6 structure necessary for interventions targeted via contact tracing. To assess diseases with a wide range of natural histories that have the potential for causing sudden, severe epidemics, we consider case studies of seven known pathogens: Ebola; hepatitis A; influenza A; Middle East Respiratory Syndrome (MERS); pertussis; SARS; and smallpox. We identify which disease characteristics and intervention attributes are most critical in deciding between quarantine and symptom monitoring, and provide a clear, general framework for understanding the consequences of isolation policies during an epidemic of known or novel pathogens.
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