Author: Xianding Deng; Wei Gu; Scot Federman; Louis Du Plessis; Oliver Pybus; Nuno Faria; Candace Wang; Guixia Yu; Chao-Yang Pan; Hugo Guevara; Alicia Sotomayor-Gonzalez; Kelsey Zorn; Allan Gopez; Venice Servellita; Elaine Hsu; Steve Miller; Trevor Bedford; Alexander Greninger; Pavitra Roychoudhury; Michael Famulare; Helen Y Chu; Jay Shendure; Lea Starita; Catie Anderson; Karthik Gangavarapu; Mark Zeller; Emily Spencer; Kristian Andersen; Duncan MacCannell; Suxiang Tong; Gregory Armstrong; Clinton Paden; Yan Li; Ying Zhang; Scott Morrow; Matthew Willis; Bela Matyas; Sundari Mase; Olivia Kasirye; Maggie Park; Curtis Chan; Alexander Yu; Shua Chai; Elsa Villarino; Brandon Bonin; Debra Wadford; Charles Y Chiu
Title: A Genomic Survey of SARS-CoV-2 Reveals Multiple Introductions into Northern California without a Predominant Lineage Document date: 2020_3_30
ID: cbc98t7x_4
Snippet: We recently developed a method called metagenomic sequencing with spiked primer enrichment (MSSPE) to rapidly enrich and assemble viral genomes directly from clinical samples (14) . Here we used this method to recover viral genomes from COVID-19 patients in Northern California and perform phylogenetic analysis to better understand the genetic diversity of SARS-CoV-2 in the US and the nature of transmission of virus lineages in the community......
Document: We recently developed a method called metagenomic sequencing with spiked primer enrichment (MSSPE) to rapidly enrich and assemble viral genomes directly from clinical samples (14) . Here we used this method to recover viral genomes from COVID-19 patients in Northern California and perform phylogenetic analysis to better understand the genetic diversity of SARS-CoV-2 in the US and the nature of transmission of virus lineages in the community.
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