Author: Courtney R. Sullivan; Catharine A. Mielnik; Sinead M. O’Donovan; Adam J. Funk; Eduard Bentea; Erica A.K. DePasquale; Zhexing Wen; Vahram Haroutunian; Pavel Katsel; Amy J. Ramsey; Jarek Meller; Robert E. McCullumsmith
Title: Connectivity analyses of bioenergetic changes in schizophrenia: Identification of novel treatments Document date: 2018_6_5
ID: ltb6l5xz_60
Snippet: In summary, we extrapolated on the abnormalities of glycolytic enzymes using Enrichr pathway analyses for panels of clustered up and downregulated genes. These analyses yield additional pathways and regulators involved in cellular processes such as cell cycle regulation and inflammatory responses. Inappropriate cell cycle regulation could contribute to metabolic deficits, while the immune system has previously been implicated in schizophrenia (89.....
Document: In summary, we extrapolated on the abnormalities of glycolytic enzymes using Enrichr pathway analyses for panels of clustered up and downregulated genes. These analyses yield additional pathways and regulators involved in cellular processes such as cell cycle regulation and inflammatory responses. Inappropriate cell cycle regulation could contribute to metabolic deficits, while the immune system has previously been implicated in schizophrenia (89) (90) (91) .
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