Author: Xiaoqiang Huang; Robin Pearce; Yang Zhang
Title: Computational Design of Peptides to Block Binding of the SARS-CoV-2 Spike Protein to Human ACE2 Document date: 2020_3_31
ID: imkeghfd_19
Snippet: However, the recent biochemical studies demonstrated that SARS-CoV-2 exhibited much stronger binding affinity to hACE2 than SARS-CoV 3, 15, 21 , implying that the homology models may not have been sufficiently accurate for binding affinity assessment based on atomic-level scoring functions, although the global folds of these models were correct......
Document: However, the recent biochemical studies demonstrated that SARS-CoV-2 exhibited much stronger binding affinity to hACE2 than SARS-CoV 3, 15, 21 , implying that the homology models may not have been sufficiently accurate for binding affinity assessment based on atomic-level scoring functions, although the global folds of these models were correct.
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