Author: Kevin Dick; Kyle K Biggar; James R Green
Title: Computational Prediction of the Comprehensive SARS-CoV-2 vs. Human Interactome to Guide the Design of Therapeutics Document date: 2020_3_31
ID: dxabs45r_4
Snippet: The scientific community has been spurred into action in response to the recent COVID-19 outbreak, building on decades of basic research characterising this virus family. Labs at the forefront of the outbreak response shared genomes of the virus in open access databases, which enabled researchers to rapidly develop tests for this novel pathogen. Other labs have shared experimentally-determined and computationally-predicted structures of some of t.....
Document: The scientific community has been spurred into action in response to the recent COVID-19 outbreak, building on decades of basic research characterising this virus family. Labs at the forefront of the outbreak response shared genomes of the virus in open access databases, which enabled researchers to rapidly develop tests for this novel pathogen. Other labs have shared experimentally-determined and computationally-predicted structures of some of the viral proteins, and still others have shared epidemiological data. We hope to contribute to the scientific effort using the latest version of our sequence-based protein-protein interaction (PPI) predictor, PIPE4 [6] in combination with another state-of-the-art PPI predictor, denoted Scoring PRotein INTeractions (SPRINT) [7] . Finally, the PIPE-Sites algorithm was used to predict the sub-sequence regions with a high likelihood of mediating the physical interaction between two given pairs [8] .
Search related documents:
Co phrase search for related documents- art state and high likelihood: 1
- art state and novel pathogen: 1, 2
- art state and open access: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14
- art state and outbreak response: 1, 2, 3
- art state and physical interaction: 1, 2
- art state and PIPE Sites algorithm: 1, 2, 3
- art state and ppi predictor: 1, 2
- art state and protein protein: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41
- art state and protein protein interaction: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12
- art state and recent outbreak: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13
- art state and scientific community: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28
- art state and scientific effort: 1
- art state and sub sequence: 1
- art state and viral protein: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19
- art state and virus family: 1, 2, 3, 4, 5, 6
- art state and virus genome: 1, 2, 3, 4, 5, 6, 7, 8, 9
Co phrase search for related documents, hyperlinks ordered by date