Author: Kevin Dick; Kyle K Biggar; James R Green
Title: Computational Prediction of the Comprehensive SARS-CoV-2 vs. Human Interactome to Guide the Design of Therapeutics Document date: 2020_3_31
ID: dxabs45r_49
Snippet: Among the 225 human proteins identified, six Human Leukocyte Antigen (HLA) class I/II histocompatibility antigens were predicted to interact with P0DTC3, the SARS-CoV-2 Protein 3a: The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.03.29.014381 doi: bioRxiv preprint Figure 8 : Landscapes of the Six Predicted HLA interactors with SARS-CoV-2 Protein 3a. The three red rectangles represent the p.....
Document: Among the 225 human proteins identified, six Human Leukocyte Antigen (HLA) class I/II histocompatibility antigens were predicted to interact with P0DTC3, the SARS-CoV-2 Protein 3a: The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.03.29.014381 doi: bioRxiv preprint Figure 8 : Landscapes of the Six Predicted HLA interactors with SARS-CoV-2 Protein 3a. The three red rectangles represent the predicted PIPE-Sites regions. Their "shifted" relative to the highlighted cells is due to the algorithm's use of a window of 20 amino acids in length that extends both to the left (along the x-axis) and upwards (along the y-axis). This implementation may also result in the predicted site extending past the coloured matrix, either to the right or above. The PIPE-Sites may overlap when numerous hits appear within close proximity, as is the case when a "band" of hits appears in the matrix.
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