Bovine noroviruses: A missing component of calf diarrhoea diagnosis

Di Felice, Elisabetta; Mauroy, Axel; Pozzo, Fabiana Dal; Thiry, Damien; Ceci, Chiara; Di Martino, Barbara; Marsilio, Fulvio; Thiry, Etienne

Noroviruses are RNA viruses that belong to the Genus Norovirus, Family Caliciviridae, and infect human beings and several animal species, including cattle. Bovine norovirus infections have been detected in cattle of a range of different ages throughout the world. Currently there is no suitable cell culture system for these viruses and information on their pathogenesis is limited. Molecular and serological tests have been developed, but are complicated by the high genetic and antigenic diversity of bovine noroviruses. Bovine noroviruses can be detected frequently in faecal samples of diarrhoeic calves, either alone or in association with other common enteric pathogens, suggesting a role for these viruses in the aetiology of calf enteritis.