Author: Valeria Lulla; Andrew E. Firth
Title: A hidden gene in astroviruses encodes a cell-permeabilizing protein involved in virus release Document date: 2019_6_6
ID: avq3zwmc_15
Snippet: After seven blind passages in Caco2 cells, two mutant viruses (pAVIC1-AUGm and pAVIC1-. CC-BY 4.0 International license author/funder. It is made available under a The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/661579 doi: bioRxiv preprint PTC1) demonstrated an ï¾1 log increase in virus titers, which was achieved via a pseudoreversion (pAVIC1-AUGm) or 5 or 8 codon deletions (pAVIC1-PTC1) (Fi.....
Document: After seven blind passages in Caco2 cells, two mutant viruses (pAVIC1-AUGm and pAVIC1-. CC-BY 4.0 International license author/funder. It is made available under a The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/661579 doi: bioRxiv preprint PTC1) demonstrated an ï¾1 log increase in virus titers, which was achieved via a pseudoreversion (pAVIC1-AUGm) or 5 or 8 codon deletions (pAVIC1-PTC1) (Fig. 3C ). All three mutations would result in restoration of XP expression, confirming its importance in virus growth.
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