Selected article for: "degradation rate and maturation rate"
Author: A. Reiser; D. Woschée; N. Mehrotra; R. Krzyszton; H. H. Strey; J. O. Rädler
Title: Correlation of mRNA delivery timing and protein expression in lipid-based transfection
  • Document date: 2019_4_13
    • ID: 9h6ctbyx_43
    Snippet: The differential equations for the model have an analytic solution for the amount of protein ( ) at time , and this solution was fitted to the data. The analytical solution of ( ) in the threestage model is Here, 0 is the amount of mRNA taken up by the cell, TL is the translation rate, is the protein maturation rate, and are the degradation rates of the mRNA and of the protein (including pre-mature eGFP), respectively, and 0 is the delivery onset.....
    Document: The differential equations for the model have an analytic solution for the amount of protein ( ) at time , and this solution was fitted to the data. The analytical solution of ( ) in the threestage model is Here, 0 is the amount of mRNA taken up by the cell, TL is the translation rate, is the protein maturation rate, and are the degradation rates of the mRNA and of the protein (including pre-mature eGFP), respectively, and 0 is the delivery onset time relative to the exposure of cells to the transfection agent.

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