Author: Ali Albsheer, Musab M.; Hussien, Ayman; Kwiatkowski, Dominic; Hamid, Muzamil Mahdi Abdel; Ibrahim, Muntaser E.
Title: The Duffy T-33C is an insightful marker of human history and admixture Cord-id: 1oo7j8c5 Document date: 2020_8_11
ID: 1oo7j8c5
Snippet: A contrasting genotype and allele frequency pattern between Africans and non-Africans in the Duffy (T-33C) locus is reported. Its near fixation in various populations suggest is no longer under natural selection, and that current distribution is possibly a relic of distant extreme selection combined with genetic drift during the out of Africa. We put this difference into the utility to infer the ancestral state of ambiguous loci in different populations.
Document: A contrasting genotype and allele frequency pattern between Africans and non-Africans in the Duffy (T-33C) locus is reported. Its near fixation in various populations suggest is no longer under natural selection, and that current distribution is possibly a relic of distant extreme selection combined with genetic drift during the out of Africa. We put this difference into the utility to infer the ancestral state of ambiguous loci in different populations.
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