Author: Louie, Raymond Hy; Luciani, Fabio
Title: Recent advances in single-cell multi-modal analysis to study immune cells. Cord-id: 1ovu9jrf Document date: 2020_12_14
ID: 1ovu9jrf
Snippet: Recent advances in single-cell technologies have enabled the profiling of the genome, epigenome, transcriptome and proteome, along with temporal and spatial information of individual cells. These technologies have provided unique opportunities to understand mechanisms underpinning the immune system, such as characterisations of the molecular cell state, how the cell state evolves along its lineage, and the impact of spatial location on cell state. In this review, we discuss how these mechanisms
Document: Recent advances in single-cell technologies have enabled the profiling of the genome, epigenome, transcriptome and proteome, along with temporal and spatial information of individual cells. These technologies have provided unique opportunities to understand mechanisms underpinning the immune system, such as characterisations of the molecular cell state, how the cell state evolves along its lineage, and the impact of spatial location on cell state. In this review, we discuss how these mechanisms have been studied through recent advances in single-cell multi-modal technologies.
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