Selected article for: "L1000 gene and LDHA knockdown signature"
Author: Courtney R. Sullivan; Catharine A. Mielnik; Sinead M. O’Donovan; Adam J. Funk; Eduard Bentea; Erica A.K. DePasquale; Zhexing Wen; Vahram Haroutunian; Pavel Katsel; Amy J. Ramsey; Jarek Meller; Robert E. McCullumsmith
Title: Connectivity analyses of bioenergetic changes in schizophrenia: Identification of novel treatments
  • Document date: 2018_6_5
    • ID: ltb6l5xz_52
    Snippet: We used iLINCS (http://ilincs.org) to retrieve knockdown signatures for each seed gene individually. Each seed gene knockdown signature (GPI knockdown signature, HK1 knockdown . CC-BY-NC-ND 4.0 International license is made available under a The copyright holder for this preprint (which was not peer-reviewed) is the author/funder. It . https://doi.org/10.1101/338392 doi: bioRxiv preprint signature, PFKM knockdown signature, PFKL knockdown signatu.....
    Document: We used iLINCS (http://ilincs.org) to retrieve knockdown signatures for each seed gene individually. Each seed gene knockdown signature (GPI knockdown signature, HK1 knockdown . CC-BY-NC-ND 4.0 International license is made available under a The copyright holder for this preprint (which was not peer-reviewed) is the author/funder. It . https://doi.org/10.1101/338392 doi: bioRxiv preprint signature, PFKM knockdown signature, PFKL knockdown signature, LDHA knockdown signature, PFKFB2 knockdown signature) is comprised of the transcriptional changes of 978 landmark genes (L1000 genes) when that seed gene is knocked down ( Figure S3 ).

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