Selected article for: "RT PCR and symptom onset"
Author: Peng, Jing; Liu, Zhi-Yong; Yu, Xiao-Juan; Chen, Xiao-Yan; Zhang, Kai; Liu, Yi; Su, Ying-Ying; Sun, Chang-Qing
Title: Antibody response in COVID-19 patients with and without re-positive RT-PCR results during the convalescent phase
  • Cord-id: 4qu3i4p3
  • Document date: 2021_6_8
    • ID: 4qu3i4p3
    Snippet: Nucleic acid testing and antibody testing data from 143 recovered COVID-19 patients during the convalescent phase were retrospectively analyzed. A total of 23 (16.1%) recovered patients re-tested positive for SARS-CoV-2 RNA by RT-PCR. Three months after symptom onset, 100% and 99.3% of the patients remained positive for total and IgG antibodies, and the antibody levels remained high. IgM antibodies declined rapidly, with a median time to seroconversion of 67 (95% CI: 59, 75) days after onset. Ap
    Document: Nucleic acid testing and antibody testing data from 143 recovered COVID-19 patients during the convalescent phase were retrospectively analyzed. A total of 23 (16.1%) recovered patients re-tested positive for SARS-CoV-2 RNA by RT-PCR. Three months after symptom onset, 100% and 99.3% of the patients remained positive for total and IgG antibodies, and the antibody levels remained high. IgM antibodies declined rapidly, with a median time to seroconversion of 67 (95% CI: 59, 75) days after onset. Approximately 25% of patients were seronegative for IgA antibodies at three months after onset. There was no statistically significant difference in antibody kinetics between patients with and without re-positive RT-PCR results during the convalescent phase. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00705-021-05132-9.

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