Author: Lynch, Maureen; Macori, Guerrino; Fanning, Séamus; O’Regan, Edel; Hunt, Eoin; O’Callaghan, Dermot; McCullagh, Brian; Jennings, Cormac; Fortune, Anne
Title: Genomic Evolution of SARS-CoV-2 Virus in Immunocompromised Patient, Ireland Cord-id: 23jqo50c Document date: 2021_9_25
ID: 23jqo50c
Snippet: We examined virus genomic evolution in an immunocompromised patient with prolonged severe acute respiratory syndrome coronavirus 2 infection. Genomic sequencing revealed genetic variation during infection: 3 intrahost mutations and possible superinfection with a second strain of the virus. Prolonged infection in immunocompromised patients may lead to emergence of new virus variants.
Document: We examined virus genomic evolution in an immunocompromised patient with prolonged severe acute respiratory syndrome coronavirus 2 infection. Genomic sequencing revealed genetic variation during infection: 3 intrahost mutations and possible superinfection with a second strain of the virus. Prolonged infection in immunocompromised patients may lead to emergence of new virus variants.
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