Author: Liu, Jia; Yan, Weiqi; Liu, Zhuojun; Han, Yizhao; Zhang, Leqiang; Yu, Jian
Title: A colloidal gold-based immunochromatographic strip for rapid detection of SARS-CoV-2 antibodies after vaccination Cord-id: 2e6yid6i Document date: 2021_6_26
ID: 2e6yid6i
Snippet: Vaccination is an important device to block the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and effectively protect the organism from pathogen infection. However, a quick and accurate technique to evaluate the immune efficacy of the Novel Coronavirus inactivated vaccine remains scarce. In this paper, the IgM-IgG antibody combined detection colloidal gold immunochromatography assay kit was optimized and developed, which can detect the efficacy of the inactivated S
Document: Vaccination is an important device to block the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and effectively protect the organism from pathogen infection. However, a quick and accurate technique to evaluate the immune efficacy of the Novel Coronavirus inactivated vaccine remains scarce. In this paper, the IgM-IgG antibody combined detection colloidal gold immunochromatography assay kit was optimized and developed, which can detect the efficacy of the inactivated SARS-CoV-2 vaccine. We collected fingertip blood samples from 3 vaccinees and 1 unvaccinated person. The results showed that the proportion of antibody was high after the second dose immunization. The IgM-IgG combined antibody assay is rapid, convenient and easy to operate. It can be used as an auxiliary method for preliminary evaluation of the antibody effect of vaccine recipients, and provide a reference index for the potential clinical application value of the vaccine.
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