Examining the Necessity of Postoperative Day-1 Review After Pars Plana Vitrectomy: A Meta-Analysis

Bheemidi, Abhinav R; Roan, Vivian D; Muste, Justin C; Singh, Rishi P

BACKGROUND AND OBJECTIVES: This study aimed to evaluate the necessity of the postoperative day-1 (POD1) review after pars plana vitrectomy. PATIENTS AND METHODS: The analysis included available literature that documented medical and surgical interventions performed on POD1 review after pars plana vitrectomy. A meta-analysis of proportions was conducted using a binomial-normal model to analyze three data sets consisting of all interventions, medical interventions, and surgical interventions. Heterogeneity and publication bias analyses were performed. RESULTS: POD1 reviews of 2,262 patients across 14 studies were examined to yield a total POD1 intervention rate estimate of 4.7% (95% confidence interval [CI], 3.0-13.9). When stratified by medical or surgical intervention, the intervention rate estimates were 4.1% (95% CI, 1.4-11.6) and 0.7% (95% CI, 0.3-1.3), respectively. The most common complication requiring postoperative intervention was elevated intraocular pressure. CONCLUSION: Given the wide confidence intervals of the estimated intervention rates, variability in postoperative practices, and range of interventions performed, the POD1 review cannot be discarded in its entirety. [Ophthalmic Surg Lasers Imaging Retina. 2021;52:513-518.].