Author: McCaw, Zachary R; Tian, Lu; Kim, Dae Hyun; Localio, A Russell; Wei, Lee-Jen
Title: Survival Analysis of Treatment Efficacy in Comparative Coronavirus Disease 2019 Studies Cord-id: 4a2xfd4d Document date: 2020_10_14
ID: 4a2xfd4d
Snippet: For survival analysis in comparative coronavirus disease 2019 trials, the routinely used hazard ratio may not provide a meaningful summary of the treatment effect. The mean survival time difference/ratio is an intuitive, assumption-free alternative. However, for short-term studies, landmark mortality rate differences/ratios are more clinically relevant and should be formally analyzed and reported.
Document: For survival analysis in comparative coronavirus disease 2019 trials, the routinely used hazard ratio may not provide a meaningful summary of the treatment effect. The mean survival time difference/ratio is an intuitive, assumption-free alternative. However, for short-term studies, landmark mortality rate differences/ratios are more clinically relevant and should be formally analyzed and reported.
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