Passive Immunity in Newborn from SARS-CoV-2 Infected Mother.

Cavaliere, Anna Franca; Marchi, Laura; Aquilini, Donatella; Brunelli, Tamara; Vasarri, Pier Luigi

BACKGROUND SARS-CoV-2 vertical transmission is an open issue. Recent reports call into question in utero or peripartum viral transmission to the offspring. Few data are available on IgG and/or IgM in newborn. Insufficient evidence is available regarding passive immunity in neonates born from SARS-CoV-2 infected women. CASE We report a case of a neonate showing the presence of blood specific IgG and the absence of IgM and negative nasopharyngeal swab. He was born from an asymptomatic SARS-CoV-2 infected mother with positive IgG and IgM. CONCLUSION The transplacental passage of specific IgG antibodies from the affected mother to the unaffected fetus highlights neonatal passive immunity. This article is protected by copyright. All rights reserved.