Selected article for: "future treatment and important role"
Author: Fang, Wanyi; Jiang, Jingrui; Su, Lei; Shu, Tong; Liu, Huan; Lai, Shenghan; Ghiladi, Reza A.; Wang, Jun
Title: The role of NO in COVID-19 and potential therapeutic strategies
  • Cord-id: 4iaknrgp
  • Document date: 2021_2_1
    • ID: 4iaknrgp
    Snippet: Nitric oxide (NO) is a free radical playing an important pathophysiological role in cardiovascular and immune systems. Recent studies reported that NO levels were significantly lower in patients with COVID-19, which was suggested to be closely related to vascular dysfunction and immune inflammation among them. In this review, we examine the potential role of NO during SARS-CoV-2 infection from the perspective of the unique physical, chemical and biological properties and potential mechanisms of
    Document: Nitric oxide (NO) is a free radical playing an important pathophysiological role in cardiovascular and immune systems. Recent studies reported that NO levels were significantly lower in patients with COVID-19, which was suggested to be closely related to vascular dysfunction and immune inflammation among them. In this review, we examine the potential role of NO during SARS-CoV-2 infection from the perspective of the unique physical, chemical and biological properties and potential mechanisms of NO in COVID-19, as well as possible therapeutic strategies using inhaled NO. We also discuss the limits of NO treatment, and the future application of this approach in prevention and therapy of COVID-19.

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