Author: Falcão, Melissa Barreto; Pamplona de Góes Cavalcanti, Luciano; Filgueiras Filho, Nivaldo Menezes; Antunes de Brito, Carlos Alexandre
Title: Case Report: Hepatotoxicity Associated with the Use of Hydroxychloroquine in a Patient with COVID-19 Cord-id: 63nmj6ok Document date: 2020_4_17
ID: 63nmj6ok
Snippet: Hydroxychloroquine (HCQ) has been used for the treatment of novel coronavirus disease (COVID-19) cases. However, evidence of efficacy remains limited, and adverse events can be associated with its use. Here, we report a case of a patient with severe COVID-19 who, after being administered HCQ, exhibited a 10-fold increase in serum levels of transaminases, followed by a rapid decrease after HCQ was withdrawn. Considering the significantly increased use of HCQ during the COVID-19 pandemic, this cas
Document: Hydroxychloroquine (HCQ) has been used for the treatment of novel coronavirus disease (COVID-19) cases. However, evidence of efficacy remains limited, and adverse events can be associated with its use. Here, we report a case of a patient with severe COVID-19 who, after being administered HCQ, exhibited a 10-fold increase in serum levels of transaminases, followed by a rapid decrease after HCQ was withdrawn. Considering the significantly increased use of HCQ during the COVID-19 pandemic, this case alerts us to the potential for HCQ to be associated with hepatotoxicity and the need to monitor liver function during HCQ therapy.
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