Doubtful precipitation of hemolysis by hydroxychloroquine in glucose‐6‐phosphate dehydrogenase deficient patient with COVID‐19 infection

Afra, T.P; Nampoothiri, Ram Vasudevan; Razmi T, Muhammed

We read with great interest the recent article by Beauverd et al.(1) on an interesting case of severe hemolysis in a patient with COVID‐19 treated with hydroxychloroquine. The authors concluded that COVID‐19 infection was possibly the initial trigger for hemolysis. However, the article also suggested that hydroxychloroquine possibly worsened the hemolysis, and further cautioned the use of hydroxychloroquine in glucose‐6‐phosphate dehydrogenase (G6PD)‐deficient patients. We would like to comment on the authors’ attribution of accentuated hemolysis to the use of hydroxychloroquine.