Author: Scheiner, Bernard; Northup, Patrick G; Lisman, Ton; Mandorfer, Mattias
Title: Author response to Letter to the Editor: 'AB0, von Willebrand factor/Factor VIII and portal vein thrombosis in decompensated cirrhosis: too late to unmask the culprit?' Cord-id: 7te3djv2 Document date: 2020_5_5
ID: 7te3djv2
Snippet: We thank Bitto and coworkers[1] for the interest in our study in which we tested the hypothesis whether ABO blood type would be a risk factor for portal vein thrombosis (PVT) in patients with advanced chronic liver disease (ACLD)[2]. In line with our findings, Bitto and coworkers provide data demonstrating that von Willebrand factor levels significantly differ between patients with O and non-O blood types in early stage ACLD, but not when they have more advanced disease[1]. These data thus confi
Document: We thank Bitto and coworkers[1] for the interest in our study in which we tested the hypothesis whether ABO blood type would be a risk factor for portal vein thrombosis (PVT) in patients with advanced chronic liver disease (ACLD)[2]. In line with our findings, Bitto and coworkers provide data demonstrating that von Willebrand factor levels significantly differ between patients with O and non-O blood types in early stage ACLD, but not when they have more advanced disease[1]. These data thus confirm that the impact of liver disease severity on VWF levels overrules the effect of blood type.
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