Selected article for: "active site and conformational change"
Author: Brent De Wijngaert; Shemaila Sultana; Chhaya Dharia; Hans Vanbuel; Jiayu Shen; Daniel vasilchuk; Sergio E Martinez; Eaazhisai Kandiah; Smita S Patel; Kalyan Das
Title: Cryo-EM structures reveal transcription initiation steps by yeast mitochondrial RNA polymerase
  • Document date: 2020_4_14
    • ID: ex3zlq38_14
    Snippet: Movie S2. Conformational change of downstream DNA and expansion of the transcription bubble. Morphing between the PIC state (gray DNA) and IC state (cyan non-template, pink template, and 2-mer RNA pppGpG and UTPaS in stick models) shows DNA bubble expansion associated with the template base-pairing with the 2-mer RNA and UTP at the polymerase active site. The downstream DNA bends by about 60° (Fig. S5) . The protein atoms are removed for clear v.....
    Document: Movie S2. Conformational change of downstream DNA and expansion of the transcription bubble. Morphing between the PIC state (gray DNA) and IC state (cyan non-template, pink template, and 2-mer RNA pppGpG and UTPaS in stick models) shows DNA bubble expansion associated with the template base-pairing with the 2-mer RNA and UTP at the polymerase active site. The downstream DNA bends by about 60° (Fig. S5) . The protein atoms are removed for clear visualization of the DNA.

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