Selected article for: "acute syndrome and low respiratory disease"
Author: Sessa, Maria; Rizzi, Marco; Gerevini, Simonetta
Title: Background
  • Cord-id: 02o0y8zh
  • Document date: 2021_3_18
    • ID: 02o0y8zh
    Snippet: Human coronaviruses, first characterized in the 1960s, are responsible for a substantial proportion of upper respiratory tract infections in children, with occasional cases of pneumonia in infants and young adults; for a few decades since their first identification, their pathogenicity has been considered to be low; non-respiratory localizations of the disease, including neurological complications, have been described as uncommon events [1]. In the new millennium, new more virulent coronaviruses
    Document: Human coronaviruses, first characterized in the 1960s, are responsible for a substantial proportion of upper respiratory tract infections in children, with occasional cases of pneumonia in infants and young adults; for a few decades since their first identification, their pathogenicity has been considered to be low; non-respiratory localizations of the disease, including neurological complications, have been described as uncommon events [1]. In the new millennium, new more virulent coronaviruses made their appearance in humans SARS-CoV, causing the Severe Acute Respiratory Syndrome (2002–2004) and MERS-CoV, causing the Middle Eastern Respiratory Syndrome (2012–ongoing); also SARS-CoV and MERS-CoV were mostly associated to respiratory disease, but different organs and body systems could be involved, including the Central Nervous System [2], as recently summarized by Verstrepen et al. [3].

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