Author: Lundstrom, Kenneth
Title: RNA-based drugs and vaccines Cord-id: 0546gio0 Document date: 2014_9_14
ID: 0546gio0
Snippet: RNA-based approaches have provided novel alternatives for modern drug discovery. The application of RNA as therapeutic agents has, until recently, been hampered by issues related to poor delivery and stability, but chemical modifications and new delivery approaches have increased progress. Moreover, the discovery of the importance of RNA in gene regulation and gene silencing has revealed new drug targets, especially related to treatment of cancer and other diseases. Recent engineering of small m
Document: RNA-based approaches have provided novel alternatives for modern drug discovery. The application of RNA as therapeutic agents has, until recently, been hampered by issues related to poor delivery and stability, but chemical modifications and new delivery approaches have increased progress. Moreover, the discovery of the importance of RNA in gene regulation and gene silencing has revealed new drug targets, especially related to treatment of cancer and other diseases. Recent engineering of small molecules designed from RNA sequences to target miRNAs opens up new possibilities in drug development. Furthermore, RNA-based vaccines have been engineered applying RNA virus vectors and non-viral delivery for vaccine development.
Search related documents:
Co phrase search for related documents- accumulation result and additional protection: 1
- acid lipid and acute respiratory syndrome coronavirus: 1, 2, 3, 4, 5, 6, 7
- acute respiratory syndrome coronavirus and additional protection: 1, 2, 3, 4, 5, 6, 7
- acute respiratory syndrome coronavirus and address important issue: 1
- acute respiratory syndrome coronavirus and liver thymus: 1
Co phrase search for related documents, hyperlinks ordered by date