Author: Sebastian J. Schreiber; Ruian Ke; Claude Loverdo; Miran Park; Priyanna Ahsan; James O. Lloyd-Smith
Title: Cross-scale dynamics and the evolutionary emergence of infectious diseases Document date: 2016_7_29
ID: hain3be0_98
Snippet: α is defined as h (0), which here is equal to η, thus for short-term infections, α = R m /R w . Since R w < 1 by assumption and R m > 1 is necessary for emergence, we always have α > 1 and so the frequency dependent dynamics at the scale of the host population can not significantly impede emergence. Now, lets consider the more difficult case of a long-term infection with a saturated phase to the within-host viral dynamics. Then.....
Document: α is defined as h (0), which here is equal to η, thus for short-term infections, α = R m /R w . Since R w < 1 by assumption and R m > 1 is necessary for emergence, we always have α > 1 and so the frequency dependent dynamics at the scale of the host population can not significantly impede emergence. Now, lets consider the more difficult case of a long-term infection with a saturated phase to the within-host viral dynamics. Then
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