Author: Lawaczeck, Rüdiger
Title: COVID-19 and Body Iron: A Survey on Phenomenological and Genetic Correlations. Cord-id: 03lz5l8t Document date: 2020_11_16
ID: 03lz5l8t
Snippet: To provide solid information about viral infection, disease, and body iron metabolism, the literature was surveyed for mutual correlations. Gender and age profiles of COVID-19 infection and disease correlate well with the profiles of serum iron and ferritin with correlation coefficients ≥ 0.75. There are further symptomatic hints that the ABO blood group system contributes to these correlations. Remarkably, the susceptibility to both the viral disease and iron dyshomeostasis can be traced back
Document: To provide solid information about viral infection, disease, and body iron metabolism, the literature was surveyed for mutual correlations. Gender and age profiles of COVID-19 infection and disease correlate well with the profiles of serum iron and ferritin with correlation coefficients ≥ 0.75. There are further symptomatic hints that the ABO blood group system contributes to these correlations. Remarkably, the susceptibility to both the viral disease and iron dyshomeostasis can be traced back to the same gene loci of the ABO blood group system. The overlapping of susceptible gene loci together with the phenomenological correlations in gender and age are strong indicators for the interrelation of body iron dyshomeostasis with COVID-19 infection and disease.
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