Author: Rajanish Giri; Taniya Bhardwaj; Meenakshi Shegane; Bhuvaneshwari R. Gehi; Prateek Kumar; Kundlik Gadhave
Title: Dark Proteome of Newly Emerged SARS-CoV-2 in Comparison with Human and Bat Coronaviruses Document date: 2020_3_14
ID: n7ylgqfu_41
Snippet: According to the intrinsic disorder predisposition analysis of ORF3b proteins, their mean PPID values in SARS-CoV-2, Human SARS CoV, and Bat CoV are 0%, 7.1%, and 23.1% respectively, as represented in Figures 8A, 8B , and 8C. MSA results ( Figure 8D ) demonstrate that ORF3b of SARS-CoV-2 is not closer to ORF3b protein of Human SARS and ORF3b protein of Bat-CoV, having a sequence similarity of only 54.6% and 59.1%, respectively. As we can see in T.....
Document: According to the intrinsic disorder predisposition analysis of ORF3b proteins, their mean PPID values in SARS-CoV-2, Human SARS CoV, and Bat CoV are 0%, 7.1%, and 23.1% respectively, as represented in Figures 8A, 8B , and 8C. MSA results ( Figure 8D ) demonstrate that ORF3b of SARS-CoV-2 is not closer to ORF3b protein of Human SARS and ORF3b protein of Bat-CoV, having a sequence similarity of only 54.6% and 59.1%, respectively. As we can see in Table 2 , there is not a single MoRF found in ORF3b of SARS-CoV-2. However, for Human SARS we identified three MoRFs (residues 32-37, 41-70, and 125-153) and for Bat CoV one MoRF at N-terminus (residues 1-38) by MoRFchibi_web server. author/funder. All rights reserved. No reuse allowed without permission.
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