Author: Rajanish Giri; Taniya Bhardwaj; Meenakshi Shegane; Bhuvaneshwari R. Gehi; Prateek Kumar; Kundlik Gadhave
Title: Dark Proteome of Newly Emerged SARS-CoV-2 in Comparison with Human and Bat Coronaviruses Document date: 2020_3_14
ID: n7ylgqfu_6
Snippet: Proteins and their PPIDs are coloured to reflect their disorder status (ordered -blue, moderately disorderedpink, highly disordered -red) Figures 2A, 2B , and 2C are 2D-disorder plots generated for SARS-CoV-2, Human SARS and Bat CoV proteins, respectively, and represent the PPID PONDR-FIT vs. PPID Mean plots. Based on their predicted levels of intrinsic disorder, proteins can be classified as highly ordered (PPID < 10%), moderately disordered (10.....
Document: Proteins and their PPIDs are coloured to reflect their disorder status (ordered -blue, moderately disorderedpink, highly disordered -red) Figures 2A, 2B , and 2C are 2D-disorder plots generated for SARS-CoV-2, Human SARS and Bat CoV proteins, respectively, and represent the PPID PONDR-FIT vs. PPID Mean plots. Based on their predicted levels of intrinsic disorder, proteins can be classified as highly ordered (PPID < 10%), moderately disordered (10% ≤ PPID < 30%) and highly disordered (PPID ≥ 30%) [46] . From the data in Table 1 , Figures 2A, 2B , and 2C, as well as the PPID based classification, we conclude that the Nucleocapsid protein from all three strains of coronavirus possesses the highest percentage of the disorder and is classified as highly disordered protein.
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