Author: Bullis, Sean S.M.; Crothers, Jessica W.; Wayne, Shawn; Hale, Andrew J.
Title: A Cautionary Tale of False-Negative Nasopharyngeal COVID-19 Testing Cord-id: 0kyf7ikr Document date: 2020_5_5
ID: 0kyf7ikr
Snippet: There remains diagnostic uncertainty regarding the sensitivity of reverse transcription polymerase chain reaction in detection of SARS-CoV-2 from nasopharyngeal specimens. We present a case where two nasopharyngeal specimens were negative, followed by a positive sputum sample. Serial testing for COVID-19 is indicated in patients with high pretest probability of disease.
Document: There remains diagnostic uncertainty regarding the sensitivity of reverse transcription polymerase chain reaction in detection of SARS-CoV-2 from nasopharyngeal specimens. We present a case where two nasopharyngeal specimens were negative, followed by a positive sputum sample. Serial testing for COVID-19 is indicated in patients with high pretest probability of disease.
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