Selected article for: "mRNA expression and RNA seq"

Author: A. Sina Booeshaghi; Lior Pachter
Title: Decrease in ACE2 mRNA expression in aged mouse lung
  • Document date: 2020_4_5
  • ID: 0pocrjvk_8
    Snippet: Our results show a decrease in ACE2 mRNA expression between young and old mice and contradict recent claims by others 13 . To understand the discrepancies in results, we examined differences in data or methodology that could lead to contradictory results (Supp. Table 1 ). We conclude that there is strong evidence in support of a decrease in ACE2 mRNA between young and old mice, and that other currently available RNA-seq datasets do not contradict.....
    Document: Our results show a decrease in ACE2 mRNA expression between young and old mice and contradict recent claims by others 13 . To understand the discrepancies in results, we examined differences in data or methodology that could lead to contradictory results (Supp. Table 1 ). We conclude that there is strong evidence in support of a decrease in ACE2 mRNA between young and old mice, and that other currently available RNA-seq datasets do not contradict this finding. We note that results in rodents may not necessarily translate to humans.

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