Author: Rajanish Giri; Taniya Bhardwaj; Meenakshi Shegane; Bhuvaneshwari R. Gehi; Prateek Kumar; Kundlik Gadhave
Title: Dark Proteome of Newly Emerged SARS-CoV-2 in Comparison with Human and Bat Coronaviruses Document date: 2020_3_14
ID: n7ylgqfu_46
Snippet: ORF7a and ORF7b proteins. Alternatively called U122, ORF7a is a type I transmembrane protein [107, 108] . It has been proven to localize in ER, Golgi, and peri-nuclear space. The presence of a KRKTE motif near the C-terminal region is needed for importing this protein from the ER to the Golgi apparatus [107, 108] . ORF7a contributes to viral pathogenesis by activating the release of pro-inflammatory cytokines and chemokines, such as IL-8 and auth.....
Document: ORF7a and ORF7b proteins. Alternatively called U122, ORF7a is a type I transmembrane protein [107, 108] . It has been proven to localize in ER, Golgi, and peri-nuclear space. The presence of a KRKTE motif near the C-terminal region is needed for importing this protein from the ER to the Golgi apparatus [107, 108] . ORF7a contributes to viral pathogenesis by activating the release of pro-inflammatory cytokines and chemokines, such as IL-8 and author/funder. All rights reserved. No reuse allowed without permission.
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