Author: Ci Song; Yan Wang; Weiqin Li; Bicheng Hu; Guohua Chen; Ping Xia; Wei Wang; Chaojun Li; Jiahao Sha; zhibin hu; Xiaoyu Yang; Bing Yao; Yun Liu
Title: Detection of 2019 novel coronavirus in semen and testicular biopsy specimen of COVID-19 patients Document date: 2020_4_4
ID: 6ujnd022_2
Snippet: Recently, two studies have answered whether 2019-nCoV could spread sexually or vertically and pose risks to the fetus and neonate among female patients [7, 8] . No evidence was showed for sexual transmission or intrauterine infection caused by vertical transmission in women who develop COVID-19 pneumonia. However, according to the recent bioinformatic evidence [9, 10] , the angiotensin-converting enzyme 2 (ACE2), a target for 2019-nCoV infection,.....
Document: Recently, two studies have answered whether 2019-nCoV could spread sexually or vertically and pose risks to the fetus and neonate among female patients [7, 8] . No evidence was showed for sexual transmission or intrauterine infection caused by vertical transmission in women who develop COVID-19 pneumonia. However, according to the recent bioinformatic evidence [9, 10] , the angiotensin-converting enzyme 2 (ACE2), a target for 2019-nCoV infection, is predominantly enriched in human testes, raising the urgent question of viral sexual transmission and paternal transmission route among males. Answer to this question is essential for formulating the principles of treatment and guidelines of sexual behavior when restored for men with 2019-nCoV infection. Therefore, to explore the possibility of sexual transmission of this contagious virus from male, we examined the viral RNA in semen and testicular biopsy specimen respectively from 12 patients in recovery and one patients died in the acute phase of 2019-nCov infection. All rights reserved. No reuse allowed without permission. author/funder, who has granted medRxiv a license to display the preprint in perpetuity.
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